Roflumilast
| File:Roflumilast.png | |
| Clinical data | |
|---|---|
| ATC code | |
| Identifiers | |
| PubChem CID | |
| DrugBank | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C17H14Cl2F2N2O3 |
| Molar mass | 403.212 g/mol |
Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor which, due to its selective inhibition of the PDE4 isoenzyme, has potential antiinflammatory and antimodulatory effects in the pulmonary system.
Karish SB, Gagnon JM. Ann Pharmacother. 2006 May 30 Template:Pharma-stub
Roflumilast(3-cyclopropylmethoxy-4 difluromethoxy-n-[3,5-dicloropyrid-4yl]-benzamide) is a selective pde4 inhibitor developed by altana pharma.Inhibition of pde4 theoretically leads to inhibition of proinflammatory mediators and the clinical effects of inhibition of bronchoconstriction,chemotaxis,and inflammation
Prashant R. Shirode Mumbai( INDIA )
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