WBR0386
| Author | [[PageAuthor::Rim Halaby, M.D. [1]]] |
|---|---|
| Exam Type | ExamType::USMLE Step 1 |
| Main Category | MainCategory::Embryology |
| Sub Category | SubCategory::Renal |
| Prompt | [[Prompt::A researcher is attempting to create developmental inhibitors of embryological components to study the embryologic origins of various tissues. While studying kidney embryology, the researcher decides to inhibit the development of the ureteric bud. As a result of his experiment, which of the following renal structures will fail to develop?]] |
| Answer A | AnswerA::Glomeruli |
| Answer A Explanation | AnswerAExp::Glomerulus is derived from the metanephros |
| Answer B | AnswerB::Cortical proximal convoluted tubule (PCT) |
| Answer B Explanation | AnswerBExp::PCT is derived from the metanephros |
| Answer C | AnswerC::Loop of Henle in the medulla |
| Answer C Explanation | AnswerCExp::Loop of Henle is derived from the metanephros |
| Answer D | AnswerD::Cortical distal convoluted tubules (DCT) |
| Answer D Explanation | AnswerDExp::DCT is derived from the metanephros |
| Answer E | AnswerE::Medullary collecting ducts |
| Answer E Explanation | AnswerEExp::Collecting ducts are derived from the ureteric bud. |
| Right Answer | RightAnswer::E |
| Explanation | [[Explanation::Ureteric bud is derived from the caudal end of the mesonephros. It gives rise to collecting ducts, renal pelvicalyceal system, and ureters. In contrast, the metanephros, which interacts with the ureteric bud, gives rise to renal structures such as glomerulus, proximal convoluted tubules, loop of Henle through the distal convoluted tubules.
Educational Objective:
The metanephros and ureteric bud interact to give rise to renal and urinary structures. The metanephros gives rise to glomerulus through the distal convoluted tubule, while the ureteric bud gives rise to collecting duct, pelvicalyceal system, and the ureters. |
| Approved | Approved::No |
| Keyword | |
| Linked Question | Linked:: |
| Order in Linked Questions | LinkedOrder:: |