WBR0427

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Author [[PageAuthor::Rim Halaby, M.D. [1] (Reviewed by Alison Leibowitz)]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Physiology
Sub Category SubCategory::Cardiology
Prompt [[Prompt::A 25-year-old male, with a history of hypertrophic cardiomyopathy (HCM), presents to the cardiologist’s office for an annual-check up. Upon physical examination, you auscultate a murmur. Which of the following bedside maneuvers will most likely increase the intensity of this patient’s murmur?]]
Answer A AnswerA::Standing from a seated position
Answer A Explanation [[AnswerAExp::Standing from a seated position, a valsalva maneuver, will increase the intensity of HCM.]]
Answer B AnswerB::Clenching fists forcefully
Answer B Explanation AnswerBExp::Clenching fists forcefully, or hand grip, will increase systemic vascular resistance and afterload. Mitral regurgitation (MR) and ventricular septal defect (VSD) murmur intensities increase with hand grip.
Answer C AnswerC::Lying in supine position and raising legs upwards
Answer C Explanation [[AnswerCExp::Lying in supine position and raising legs upwards is the opposite of a valsalva maneuver. It will increase preload and decrease the intensity of the HCM murmur.]]
Answer D AnswerD::Rapid squatting
Answer D Explanation AnswerDExp::Rapid squatting increases preload and afterload, but decreases the intensity of the HCM murmur.
Answer E AnswerE::Lying in the left lateral decubitus position
Answer E Explanation [[AnswerEExp::Lying in the lateral decubitus position aids in the identification of mitral stenosis (MS), commonly a complication of rheumatic heart disease and S3 sounds, which are low frequency sounds that occur in late diastole. Best heard using the bell of a stethoscope, S3 frequently manifests with heart failure in the elderly. S3 can be a normal finding in children and pregnant women.]]
Right Answer RightAnswer::A
Explanation [[Explanation::A valsalva maneuver, characterized by decreasing venous return and preload, may occur when a patient stands from a seated position. Most heart murmurs decrease in intensity upon valsalva maneuvers with the exception of mitral valve prolapse (MVP) and HCM.

Educational Objective: A valsalva maneuver, characterized by decreasing venous return and preload, may occur when a patient stands from a seated position. Most heart murmurs decrease in intensity upon valsalva maneuvers with the exception of mitral valve prolapse (MVP) and HCM.
References: First Aid 2014 page 272]]

Approved Approved::Yes
Keyword WBRKeyword::Valsalva maneuver, WBRKeyword::murmur, WBRKeyword::hypertrophic cardiomyopathy, WBRKeyword::HCM, WBRKeyword::preload, WBRKeyword::cardiology, WBRKeyword::cardiovascular
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Order in Linked Questions LinkedOrder::