FLAG regimen

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords: IDA-FLAG Regimen; Idarubicin-Fludarabine-AraC/G-CSF Regimen

Overview

FLAG regimen refers to a regimen consisting of idarubicin, fludarabine, high-dose cytarabine (AraC) and filgrastim (G-CSF), used as a remission-induction treatment for relapsed or refractory childhood acute myeloid leukemia (AML)

Regimen

IDAIdarubicin

FLFludarabine

ACytarabine (AraC)

GFilgrastim (G-CSF)

Indications

• Relapsed or refractory childhood acute myeloid leukemia (AML)