Tuaminoheptane

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Tuaminoheptane
Clinical data
ATC code
Identifiers
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC7H17N
Molar mass115.217 g/mol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Tuaminoheptane (or tuamine) is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor.[1] However it can cause skin irritation,[2] which limits its usefulness as a nasal decongestant. Side effects can include acute glaucoma, tachycardia and hypertension.[2]

References

  1. ↑ Delicado EG, Fideu MD, Miras-Portugal MT, Pourrias B, Aunis D. Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells. Biochemical Pharmacology. 1990 Aug 15;40(4):821-5.
  2. ↑ Raoux M, Colomban C, Delmas P, Crest M. The amine-containing cutaneous irritant heptylamine inhibits the volume-regulated anion channel and mobilizes intracellular calcium in normal human epidermal keratinocytes. Molecular Pharmacology. 2007 Jun;71(6):1685-94.

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