Melperone

Melperone

File:Melperone skeletal.svg
Clinical data
Routes of administration	Oral, intramuscular injection
ATC code	N05AD03 (WHO)
Pharmacokinetic data
Metabolism	Hepatic (inhibits CYP2D6)
Elimination half-life	3–4 hours (oral) 6 hours (IM)
Identifiers
IUPAC name 1-(4-fluorophenyl)-4-(4-methyl-1-piperidyl)butan-1-one
CAS Number	3575-80-2
PubChem CID	15387
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C16H22FNO
Molar mass	263.35 g/mol

Melperone (INN, also known as methylperone) is a butyrophenone atypical antipsychotic. It is sold under the trade names Buronil, Burnil, and Eunerpan.

Chemistry

• Appearance: White, crystalline odorless powder
• Solubility: Freely soluble in water. Freely soluble in ethanol 99.5% and chloroform. Practically insoluble in diethyl ether.
• Melting Point: 205-210C
• pH (1% in water): 4.5-6.5
• Stability: 48 months

It is a white crystalline powder that is manufactured by Dupont Chemoswed (Sweden). It is a butyrophenone (1-(4-Fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone hydrochloride).

External links

• PubChem Substance
• Clinical trial number NCT00125138 at ClinicalTrials.gov