Interferon alfa-2a
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rabin Bista, M.B.B.S. [2]
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Overview
Interferon alfa-2a is a antiviral that is FDA approved for the treatment of RECURRENT VIRAL INFECTIONS. Common adverse reactions include black stools, chills, cough, fever, irritability.
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
Indications
- RECURRENT VIRAL INFECTIONS
Directions
Take 15 minutes before meals. Adults and children 12 years and older 20 drops twice a day in a little water. Hold in the mouth for about 30 seconds then swallow.
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Interferon alfa-2a in adult patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Interferon alfa-2a in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
Indications
RECURRENT VIRAL INFECTIONS
Directions
Children between 12 years and 6 years of age 10 drops twice a day in a little water. Hold in the mouth for about 30 seconds then swallow. Children under 6 years 5 drops twice a day in a glass of water.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Interferon alfa-2a in pediatric patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Interferon alfa-2a in pediatric patients.
Contraindications
There is limited information regarding Interferon alfa-2a Contraindications in the drug label.
Warnings
- Stop use and ask doctor if symptoms worsen or persist more than 3 days
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Clinical Trial Experience of Interferon alfa-2a in the drug label.
Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous
Postmarketing Experience
black stools, chills, cough, fever, irritability
Drug Interactions
- Drug
- Description
Use in Specific Populations
Pregnancy
- Pregnancy Category
- Australian Drug Evaluation Committee (ADEC) Pregnancy Category
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Interferon alfa-2a in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Interferon alfa-2a during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Interferon alfa-2a with respect to nursing mothers.
Pediatric Use
There is no FDA guidance on the use of Interferon alfa-2a with respect to pediatric patients.
Geriatic Use
There is no FDA guidance on the use of Interferon alfa-2a with respect to geriatric patients.
Gender
There is no FDA guidance on the use of Interferon alfa-2a with respect to specific gender populations.
Race
There is no FDA guidance on the use of Interferon alfa-2a with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Interferon alfa-2a in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Interferon alfa-2a in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Interferon alfa-2a in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Interferon alfa-2a in patients who are immunocompromised.
Administration and Monitoring
Administration
- Oral
Monitoring
There is limited information regarding Monitoring of Interferon alfa-2a in the drug label.
IV Compatibility
There is limited information regarding IV Compatibility of Interferon alfa-2a in the drug label.
Overdosage
There is limited information regarding Overdose of Interferon alfa-2a in the drug label.
Pharmacology
There is limited information regarding Interferon alfa-2a Pharmacology in the drug label.
Mechanism of Action
Structure
- ACTIVE INGREDIENT
INTERFERON ALFA-2A 4C INACTIVE INGREDIENT Ethyl Alcohol 30%
Pharmacodynamics
There is limited information regarding Pharmacodynamics of Interferon alfa-2a in the drug label.
Pharmacokinetics
There is limited information regarding Pharmacokinetics of Interferon alfa-2a in the drug label.
Nonclinical Toxicology
There is limited information regarding Nonclinical Toxicology of Interferon alfa-2a in the drug label.
Clinical Studies
There is limited information regarding Clinical Studies of Interferon alfa-2a in the drug label.
How Supplied
Storage
There is limited information regarding Interferon alfa-2a Storage in the drug label.
Images
Drug Images
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Package and Label Display Panel
PRINCIPAL DISPLAY PANEL
This image is provided by the National Library of Medicine.
Ingredients and Appearance
This image is provided by the National Library of Medicine.
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Patient Counseling Information
There is limited information regarding Patient Counseling Information of Interferon alfa-2a in the drug label.
Precautions with Alcohol
- Alcohol-Interferon alfa-2a interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
Brand Names
- GUNA-INF ALPHA®[1]
Look-Alike Drug Names
There is limited information regarding the look alike drug names.
Drug Shortage Status
Price
References
The contents of this FDA label are provided by the National Library of Medicine.
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