Lassa fever other diagnostic studies
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Lassa fever Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Synonyms and keywords: Lassa hemorrhagic fever; LHF
Overview
Other Diagnostic Studies
Listed below are some of the diagnostic test used to confirm Lassa fever.[1]
| Diagnostic Test | Samples required | Preparation & Storage | Detects |
| ELISA (Serology) | Serum or plasma | Freeze or refrigerate | Detects Viral antigen, IgM and IgG antibody |
| Polymerase Chain Reaction(PCR) | Serum or plasma or tissues (fresh frozen) | Freeze or refrigerate | Detects DNA, RNA (genetic material) from virus |
| Immunohisto-chemistry | Liver biopsy from fatal cases | Fix in formalin and store or transport in room temperature | Detects viral antigen in cells |
| Immunohisto-chemistry | Tissue biopsy from fatal cases | Fix in formalin and store or transport in room temperature | Detects viral antigen in cells |
| Immunohisto-chemistry | Skin biopsy from fatal cases | Fix in formalin and store or transport in room temperature | Detects viral antigen in cells |
Data from the Center of Disease Control and Prevention