Cadaveric blood

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cadaveric blood is the blood from a dead body. It has been shown that this blood can be transfused to a living person, though this has never been widely practiced except by a few Soviet groups. Research surrounding this process culminated in the creation of the first American blood bank by Dr. Bernard Fantus in 1937.

History

In 1929, professor Shamov of Kharkov in the USSR demonstrated the lack of toxicity of cadaveric blood. Russian surgeon Sergei Yudin pioneered transfusions of cadaveric blood, performing the first successful transfusion on March 23, 1930. Yudin reported his first seven clinical transfusions with cadaveric blood at the Fourth Congress of Ukrainian Surgeons at Kharkov in September 1930. Following the discovery that cadaveric blood could be stored safely, serological tests and bacteriological examinations were done. However, cadaveric blood never became widely used. The experiments and research surrounding cadaveric blood transfusions led to the development of “a variety of means and methods for the collection, preservation, and storage of blood for transfusion, all which may be grouped under the generic term of “the blood bank." Dr. Bernard Fantus modified the notion of cadaveric blood transfusions by preserving the blood of healthy living persons with preservatives and anticoagulants. By incorporating refrigeration into the preservation process, Dr. Fantus established the first US “blood bank” at Chicago's Cook County Hospital added in 1937 .[1]

References

  • [Robert A. Kilduffe and Michael DeBakey, 1942]
    • Shamov VN and Kostriukov M. Questions of homoplasty from the cadaver. Blood transfusion from cadaver, Trudi Ukrain. Suezda. Khir. 1929;18:184.
    • Shamov WN. The transfusion of stored cadaver blood Lancet 1937; 2, August 7:306-309
    • Judine S. La transfusion du sang de cadavre á l'homme. Paris: Masson et Cie, 1933.
    • Yudin S. Transfusion of stored cadaver blood. Practical consideration: The first thousand cases. Lancet 1937;2:361 - 6.
    • Yudin S. Transfusion of cadaver blood. JAMA 1936;106:997-9.
    • Swan H, Schechter D. The transfusion of blood from cadavers. A historical review. Surgery 1962;52:545 - 1962.
    • Kilduffe R, DeBakey M. The blood bank and the technique and therapeutics of transfusion. St. Louis: The C.V.Mosby Company, 1942, pp.196-197
    • Kevorkian J, Marra JJ. Transfusion of Human Corps Blood without Additives.Transfusion. 1964;4:112-7.


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