Hantavirus
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Diagnosis |
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Treatment |
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Case Studies |
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Hantavirus On the Web |
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American Roentgen Ray Society Images of Hantavirus |
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 Transmission electron micrograph of the Sin Nombre Hantavirus
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Andes virus (ANDV) |
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WikiDoc Resources for Hantavirus |
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Articles |
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Most recent articles on Hantavirus |
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Media |
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Evidence Based Medicine |
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Clinical Trials |
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Ongoing Trials on Hantavirus at Clinical Trials.gov Clinical Trials on Hantavirus at Google
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Guidelines / Policies / Govt |
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US National Guidelines Clearinghouse on Hantavirus
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Books |
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News |
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Commentary |
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Definitions |
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Patient Resources / Community |
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Patient resources on Hantavirus Discussion groups on Hantavirus Patient Handouts on Hantavirus Directions to Hospitals Treating Hantavirus Risk calculators and risk factors for Hantavirus
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Healthcare Provider Resources |
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Causes & Risk Factors for Hantavirus |
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Continuing Medical Education (CME) |
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International |
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Business |
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Experimental / Informatics |
Overview
Hantaviruses belong to the bunyaviridae family of viruses. There are 5 genera within the bunyaviridae family: bunyavirus, phlebovirus, nairovirus, tospovirus, and hantavirus. Each is made up of negative-sensed, single-stranded RNA viruses. All these genera include arthropod-borne viruses, with the exception of hantavirus, which is a genus of rodent-borne agents.
The word hantavirus is derived from the Hantan River, where the Hantaan virus (the etiologic agent of Korean hemorrhagic fever) was first isolated by Dr. Lee Ho-Wang. The disease associated with Hantaan virus is called Korean hemorrhagic fever (a term that is no longer in use) or hemorrhagic fever with renal syndrome (HFRS), a term that is accepted by the World Health Organization.
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Treatment
- Hanta virus treatment[1]
- Supportive therapy
- ICU management should include careful assessment, monitoring and adjustment of volume status and cardiac function, including inotropic and vasopressor support if needed.
- Fluids should be administered carefully due to the potential for capillary leakage.
- Supplemental oxygen should be administered if patients become hypoxic.
- Equipment and materials for intubation and mechanical ventilation should be readily available since onset of respiratory failure may be precipitous.
- Note (1): There is no specific treatment or cure for hantavirus infection.
- Note (2): Treatment of patients with HPS remains supportive in nature.
- Note (3): Patients should receive appropriate, broad-spectrum antibiotic therapy while awaiting confirmation of a diagnosis of HPS. Care during the initial stages of the disease should include antipyretics and analgesia as needed.
- Note (4): If there is a high degree of suspicion of Hantavirus pulmonary syndrome, patients should be immediately transferred to an emergency department or intensive care unit (ICU) for close monitoring and care.
- Note (5): if the individual is experiencing fever and fatigue and has a history of potential rural rodent exposure, together with shortness of breath, would be strongly suggestive of Hantavirus pulmonary syndrome.
External links
- "Hantaviruses, with emphasis on Four Corners Hantavirus" by Brian Hjelle, M.D., Department of Pathology, School of Medicine, University of New Mexico
- CDC's Hantavirus Information page
- Kruger DH, Ulrich R, Lundkvist A (2001) "Hantavirus infections and their prevention", Microbes And Infection 3 (13): 1129-1144