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The development of a rheumatic fever episode depends on the involved host being highly autoimmunologically sensitized to autoantigens exhibited by Streptococcus pyogenes to its host during prior Streptococcus pyogenes infectious episodes, so a decrease in the frequency and virulence of infections by Streptococcus pyogenes in a society can cause rheumatic fever, as a disease entity, to be less frequent and less severe.


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  1. A line break in an item is done with HTML
    like this.
  2. Just breaking the line will accidentally end the list

like this.

  1. This was supposed to be item 3, not a new list.