Uterine cancer differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Uterine cancer Microchapters
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Differentiating Uterine cancer from other Diseases
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Differentiating Uterine cancer from other Diseases

• In early disease, uterine cancer must be differentiated from other diseases causing endometrial thickening:

• benign endometrial proliferation
• endometrial hyperplasia
• endometrial polyp
• submucosal uterine leiomyoma

• Differential considerations for advanced lesions include:

• uterine sarcoma(s)
• endometrial stromal sarcoma (ESS)
• leiomyosarcoma of the uterus
• malignant mixed Mullerian tumour (MMMT) of the uterus
• uterine lymphoma: rare
• primary uterine lymphoma
• secondary uterine involvement with lymphoma
• cervical cancer with uterine invasion
• metastasis to the uterus from a non gynaecologcial malignancy: rare

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