Urethral cancer overview
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Urethral cancer is a rare type of cancer originating from the urethra. It is more common in women than in men. Types of urethral cancer include transitional cell carcinoma, squamous cell carcinoma, and adenocarcinoma. It is also a disease in which cancer cells form in the tissues of the urethra.
Classification
Urethral cancer may be classified according to cell typies into 3 subtypes: transitional cell, squamous cell, and adenocarcinoma. It may also be classified into distal urethral cancer, proximal urethral cancer and urethral cancer associated with invasive bladder cancer.
Causes
Urethral cancer may be caused by an infection of human papillomavirus.
Differential diagnosis
Urethral cancer must be differentiated from bladder cancer, cervical cancer, bladder stones, ureteral stones, cystitis, neurogenic bladder, and urethritis.
Epidemiology and Demographics
Urethral cancer is a rare disease that tends to affect African Americans. The incidence is approximately 0.43 per 100,000 in the united states for men, and approximately 0.15 per 100,000 for women.