Hodgkin's lymphoma medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
The predominant therapy for Hodgkin's lymphoma is chemotherapy. Adjunctive radiation may be required.
Medical Therapy
The choice of treatment depends on the age, sex, bulk, and the histological subtype of the disease.
- Patients with early stage disease (IA or IIA) are effectively treated with radiation therapy or chemotherapy.
- Patients with later disease (III, IVA, or IVB) are treated with combination chemotherapy alone.
- Patients of any stage with a large mass in the chest are usually treated with combined chemotherapy and radiation therapy.
Chemotherapy
- Drug Regimen: (MOPP) Mustargen AND Oncovin AND Prednisone AND Procarbazine
- Drug Regimen: (ABVD) Adriamycin AND Bleomycin AND Vinblastine AND Dacarbazine
- Drug Regimen: (Stanford V) Adriamycin AND Bleomycin AND Vinblastine AND Mechlorethamine AND Etoposide AND Prednisone AND Radiation therapy
- Drug Regimen: (BEACOPP) Bleomycin AND Etoposide AND Adriamycin AND Cyclophosphamide AND Oncovin AND Procarbazine AND Prednisone
Radiotherapy
- Radiation oncologists deliver external beam radiation therapy to the lymphoma from a machine called linear accelerator which produces high energy X Rays and electrons. Patients usually describe treatments as painless and similar to getting an X-ray. Treatments last less than 30 minutes each.
- For lymphomas, there are a few different ways radiation oncologists target the cancer cells.
- Involved field radiation is when the radiation oncologists give radiation only to those parts of the patient's body known to have the cancer. Very often, this is combined with chemotherapy.
- Radiation therapy directed above the diaphragm to the neck, chest and/or underarms is called mantle field radiation.
- Radiation to below the diaphragm to the abdomen, spleen and/or pelvis is called inverted-Y field radiation.
- Total nodal irradiation is when the therapist gives radiation to all the lymph nodes in the body to destroy cells that may have spread.[1]
References
- ↑ "RTanswers.com". RTanswers.com. 2010-12-03. Retrieved 2012-08-26.