Non-Hodgkin lymphoma risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
The risk factors in the development of Hodgkin's lymphoma are Epstein-Barr virus, family history, HIV infection. Other possible risk factors include genetics, infectious mononucleosis,autoimmune diseases, immunodeficiency, tobacco, and socio-economic status and family features.
Risk Factors
The risk factors in the development of Hodgkin's lymphoma are Epstein-Barr virus, family history, HIV infection. Other possible risk factors include genetics, infectious mononucleosis,autoimmune diseases, immunodeficiency, tobacco, and socio-economic status and family features.[1]
| Known risk factors | Possible risk factors |
|---|---|
| Weakened immune system | Family history of Non-Hodgkin lymphoma |
| Autoimmune disorders | Exposure to pesticides |
| Certain infections | Exposure to trichloroethylene |
| Previous cancer treatment | Diet |
| Obesity | |
| Hair dyes | |
| Occupational exposures |
The following are some of the risk factors associated with this disease:
- Age/sex. The likelihood of getting non-Hodgkin's lymphoma increases with age and is more common in men than in women.
- Weakened immune system (AIDS-related lymphoma). Non-Hodgkin's lymphoma is more common among people with inherited immune deficiencies, autoimmune diseases, or HIV/AIDS, and among people taking immunosuppressant drugs following organ transplants. (see Post-transplant lymphoproliferative disorder)
- Viruses. Human T-lymphotropic virus type I (HTLV-1) and Epstein-Barr virus are two infectious agents that increase the chance of developing non-Hodgkin's lymphoma.
- Environment. People who work extensively with or are otherwise exposed to certain chemicals, such as pesticides, solvents, or fertilizers, have a greater chance of developing non-Hodgkin's lymphoma.
People who are concerned about non-Hodgkin's lymphoma should talk with their doctor about the disease, the symptoms to watch for, and an appropriate schedule for checkups. The doctor's advice will be based on the person's age, medical history, and other factors.