Glioma natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The prognosis of glioma is poor.

Complications

==Prognosis==\ The prognosis for glioma depend on the following:

• Type and grade of the tumor
• Tumor is in the brain or spinal cord
• Whether the tumor can be removed by surgery
• Whether cancer cells remain after surgery
• Whether there are certain changes in the chromosomes
• Whether the cancer has just been diagnosed or has recurred.
• The patient's general health.

• Gliomas are rarely curable.
• The prognosis for patients with high-grade gliomas is generally poor, and is especially so for older patients. Of 10,000 Americans diagnosed each year with malignant gliomas, about half are alive one year after diagnosis, and 25% after two years.
• Those with anaplastic astrocytoma survive about three years.
• Glioblastoma multiforme has a worse prognosis with less than a 12-month average survival after diagnosis, though this has extended to 14 months with more recent treatments.