Osteosarcoma MRI

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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MRI

• MRI is proving essential in accurate local staging and assessment for limb sparing resection, particularly for evaluation of intraosseous tumor extension and soft-tissue involvement.
• Assessment of the growth plate is also essential as up to 75-88% of metaphyseal tumors do cross the growth plate into the epiphysis.
• On MRI, signal characteristics of osteosarcoma include:

T1:

• Soft tissue, non-mineralized component: intermediate signal intensity.
• Mineralized/ossified components: low signal intensity.
• Peri-tumoral edema: intermediate signal intensity.
• Scattered regions of haemorrhage will have variable signal.

T2:

• Soft tissue non-mineralised component: high signal intensity.
• Mineralised/ossified components: low signal intensity.
• peri-tumoral oedema: high signal intensity.

T1 C+ (Gd):

• Solid components show considerable enhancement.

Images courtesy of RadsWiki

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  MRI T1
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  MRI T1
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  MRI T1 post gad
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  MRI T1 post gad
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  MRI T2 fat sat
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  MRI T2 fat sat