Osteosarcoma biopsy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]

Biopsy

• Biopsy of osteosarcoma is important for confirming the diagnosis and for determining histologic subtype.
• Biopsy may be performed percutaneously with fine- or wide-bore needles, or through a formal incision.
• More invasive methods carry a higher risk of complications and contamination of tissue planes. Each year 30% of limbs are lost through inappropriate biopsy site and technique. In principle, biopsies should be performed at a tumor center by a specialist in tumor surgery.