Burkitt's lymphoma causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Assistant Editor-in-Chief: Soumya Sachdeva, Sowminya Arikapudi, M.B,B.S. [2]
Overview
Causes
Burkitt's lymphoma is caused by translocation between chromosomes 8 and 14 or one of its variants [t(2;8)] or t(8;22)[c-myc and κ light chain gene). Demonstration of surface expression of immunoglobulin and any one of the above cytogenetic abnormalities is confirmatory.