Medulloblastoma medical therapy
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Medulloblastoma Microchapters |
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Diagnosis |
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Treatment |
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Case studies |
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Medulloblastoma medical therapy On the Web |
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American Roentgen Ray Society Images of Medulloblastoma medical therapy |
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Risk calculators and risk factors for Medulloblastoma medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Medical Therapy
- The algorithm below summarize the management approach for medulloblastoma patients:[1]
Maximal safe surgery | |||||||||||||||||||
Histopathological analysis | |||||||||||||||||||
Thorough staging | |||||||||||||||||||
Optimal risk stratification | |||||||||||||||||||
Radiotherapy and chemotherapy according to the risk stratification criteria | |||||||||||||||||||
Radiation Therapy
- Radiotherapy is the mainstay of treatment for medulloblastoma.[2]
- Radiotherapy for medulloblastoma must be started within 6 weeks following surgery.
- The main radiotherapy techniques used in the management of medulloblastoma patients include:
- Conventional radiotherapy technique
- Intensity modulated radiotherapy technique
- Three dimensional radiotherapy technique
- Three dimensional radiotherapy technique demonstrated better outcomes when compared to conventional and intensity modulated radiotherapy techniques.
- As medulloblastoma tends to spread along the cerebrospinal fluid, it is recommended to deliver a craniospinal irradiation with a boost to the posterior fossa.
Chemotherapy
References
- ↑ von Hoff K, Rutkowski S (2012). "Medulloblastoma". Curr Treat Options Neurol. 14 (4): 416–26. doi:10.1007/s11940-012-0183-8. PMID 22622599.
- ↑ Bartlett F, Kortmann R, Saran F (2013). "Medulloblastoma". Clin Oncol (R Coll Radiol). 25 (1): 36–45. doi:10.1016/j.clon.2012.09.008. PMID 23245832.