Gestational trophoblastic neoplasia surgery

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Template:Choriocarcinoma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]

Overview

Surgery is the mainstay of treatment for choriocarcinoma.[1][2]

Surgery

Hysterectomy

Surgery is one of the main treatments for GTD.

  • Indication
  • As the primary treatment for GTD
  • Recurrence of GTD after other treatments

Hysterectomy

  • Hysterectomy may be offered to women with malignant GTD that has not spread outside of the uterus and who no longer wish to have children.
  • Hysterectomy may also be recommended to women with malignant GTD that does not respond to chemotherapy.
  • Hysterectomy is the primary treatment for women with placental site trophoblastic tumours because this type of cancer does not respond well to chemotherapy.

Surgery to remove metastases

  • Surgery may be done for GTD that has spread to distant sites in the body, such as the brain, intestines, kidney, liver, lungs and spleen.
  • In the case of brain metastases, surgery may only be done if a tumor is close to the surface of the brain.

References

  1. ↑ Low-Risk Gestational Trophoblastic Neoplasia (FIGO Score 0–6) Treatment. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq/#section/_326 Accessed on October 8, 2015
  2. ↑ High-Risk Gestational Trophoblastic Neoplasia (FIGO Score ≥7) Treatment. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq/#section/_328 Accessed on October 8, 2015

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