Anaplastic large cell lymphoma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Anaplastic large cell lymphoma is a common disease that tends to affect children or young adults. Males are more commonly affected with anaplastic large cell lymphoma than females.[1]
Epidemiology and Demographics
Age[1]
- Patients of all age groups may develop anapastic large cell lymphoma
- Anaplastic large cell lymphoma is a common disease that tends to affect children or young adults
- Anaplastic large cell lymphoma, ALK-positive usually affects younger individuals
- Anaplastic large cell lymphoma, ALK-negative usually affects older individuals
Gender[1]
- Males are more commonly affected with anaplastic large cell lymphoma than females
Epidemiology and Demographics
ALK negative ALCL represents 2%-3% of all non-Hodgkin's lymphomas (NHL) and 12% of all T-cell NHL.[2]
Age
ALK negative ALCL affects primarily adults between 40-60 years old.
Gender
There is a modest male predominance in the prevalence of the disease.[3]
ALK positive anaplastic large cell lymphoma affects primarily young (between 10 and 29 years), male patients[4] and accounts for 3% of all NHL, 40% of all large cell lymphomas[5] and 10%-20% of childhood lymphomas.[6]
According to a study on 1,320 cases of peripheral T-cell lymphomas and NK cell lymphomas between 1990 and 2002 in 22 different centers, ALK-Positive ALCL is the fifth most common type of peripheral T cell lymphoma (6.6% of total patients).[7] In the United states, ALK-Positive ALCL is the most frequent type of peripheral T-cell lymphoma.
References
- ↑ 1.0 1.1 1.2 Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 7, 2015
- ↑ "Anaplastic large cell lymphoma, ALK-negative".
- ↑ Swerdlow, Steven (2008). WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon, France: International Agency for Research on Cancer. ISBN 9789283224310.
- ↑ Stein H, Foss HD, Dürkop H, Marafioti T, Delsol G, Pulford K; et al. (2000). "CD30(+) anaplastic large cell lymphoma: a review of its histopathologic, genetic, and clinical features". Blood. 96 (12): 3681–95. PMID 11090048.
- ↑ "ALK+ Lymphoma: Clinico-Pathological Findings and Outcome".
- ↑ "ALK+ Lymphoma: Clinico-Pathological Findings and Outcome".
- ↑ "International Peripheral T-Cell and Natural Killer/T-Cell Lymphoma Study: Pathology Findings and Clinical Outcomes" (PDF).