Retinoblastoma historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

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Overview

Retinoblastoma was first described in 1809 by James Wardrop.

Historical Perspective

• Retinoblastoma was first described in 1809 by James Wardrop.
• In 1899, Flexner and Wintersteiner were the first to discover the association between tumor rosettes and photoreceptors of the adult retina.

• In 1920s Verhoeff claimed that the tumor arose from embryonic retinal cells and hence proposed the name "retinoblastoma".