Cystic nephroma pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
Microscopic Pathology
The characteristics of cystic nephromas include:
- Cysts lined by a simple epithelium with a hobnail morphology (i.e. the nuclei of the cyst lining epithelium bulges into the lumen of the cysts)
- Ovarian-like stroma
- Spindle cell morphology
- Basophilic cytoplasm
Cystic nephromas have an immunostaining pattern like ovarian stroma; they are positive for:
- Estrogen receptor (ER)
- Progesterone receptor (PR)
- CD10