Sandbox: DDx Kidney mass
- 10-30 yo sickle cell trait patients
- May have gross hematuria, back/flank pain, weight loss, and fever
- Palpable renal mass
- Lymphadenopathy
- Centrally located infiltrative mass invading the renal sinus
- Peripheral caliectasis
- Smaller peripheral satellite nodules
- Heterogeneous enhancement on CT
- Heterogeneous echotexture on US
- Solid, reticular, or tubular growth pattern
- Hyperchromatic nucleus with a prominent nucleoli
- Invasion of vessels and lymphatics
- Desmoplastic stroma, central intratumoral neutrophils with a rim of lymphocytes
- Hemorrhagic, necrosis, and increased mitotic figures
Nonmalignant causes
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying