Myelodysplastic syndrome differential diagnosis
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Differentiating Myelodysplastic syndrome from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
Myelodysplastic syndrome must be differentiated from other diseases that cause anemia, neutropenia, and thrombocytopenia, such as vitamin deficiencies, toxic exposure, biologic agents, heavy metals, chemotherapy, and infections.[1][2][3]
Myelodysplastic syndrome differential diagnosis
Myelodysplastic syndrome must be differentiated from other diseases that cause anemia, neutropenia, and thrombocytopenia, such as:[1][2][3]
Inherited cytopenia
- Shwachman-Diamond syndrome
- Large granular lymphocytosis
- Parovirus B19 infection
- Myeloproliferative neoplasms
- Congenital hematopoietic disorder
- Congenital dyserythropoietic anemia
Acquired cytopenia
- Paroxysmal nocturnal hemoglobinuria
- Toxic exposures
- Biologic agents
- Heavy metals
- Chemotherapy
Reactive Cytopenia
- Nutritional deficiency
- Vitamin B12 defeciency
- Folate defeciency
- Infections
References
- ↑ 1.0 1.1 Differential diagnosis of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 9, 2015
- ↑ 2.0 2.1 Merrill, Andrea L.; Smith, Hedy (2011). "Myelodysplastic Syndrome and Autoimmunity: A Case Report of an Unusual Presentation of Myelodysplastic Syndrome". Case Reports in Hematology. 2011: 1–4. doi:10.1155/2011/560106. ISSN 2090-6560.
- ↑ 3.0 3.1 DeZern, A. E.; Sekeres, M. A. (2014). "The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure". The Oncologist. 19 (7): 735–745. doi:10.1634/theoncologist.2014-0056. ISSN 1083-7159.