Chondroma pathophysiology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

Enchondromas arise from rests of growth plate cartilage or chondrocytes that are normally involved in the production and maintainence of the cartilaginous matrix, which consists mainly of collagen and proteoglycans.[1][2] On gross pathology, small (usually less than 3 cm), translucent, grey blue and nodular lesions are characteristic findings of enchondroma.[3]


Juxta-cortical chondromas (also known as periosteal chondromas) are rare benign chondral tumours that arise from the periosteum of tubular bones.[4]



Pathophysiology

Enchondromas arise from rests of growth plate cartilage/chondrocytes that subsequently proliferate and slowly enlarge and are composed of mature hyaline cartilage. Hence, they are seen in any bone formed from cartilage.


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References

  1. Enchondroma. Radiopedia. http://radiopaedia.org/articles/enchondroma Accessed on December 15, 2015
  2. Chondrocytes. Wikipedia. https://en.wikipedia.org/wiki/Chondrocyte. Accessed on December 16, 2015.
  3. Enchondroma. Radiopedia. http://radiopaedia.org/articles/enchondroma Accessed on December 15, 2015
  4. Juxta-cortical chondroma. Radiopedia. http://radiopaedia.org/articles/juxta-cortical-chondroma Accessed on December 15, 2015


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