Escherichia coli enteritis differential diagnosis
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Differentiating Escherichia coli enteritis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Serge Korjian M.D., Yazan Daaboul, M.D.
Overview
Differentiating Escherichia coli Enteritis from other Diseases
- Enteritis caused by E. coli must be differentiated from other causes of acute diarrhea (with or without blood) and abdominal pain.
- Differential diagnosis of E. coli enteritis includes the following:
Infectious Differential Diagnosis
The following are the infectious differential diagnoses of E. coli enteritis:
- Other bacterial infections (see table below)
- Viral infections (e.g. norovirus infection, HIV infection)
- Fungal infections (e.g. Candida spp.)
- Parasites (Giardia spp., E. histolytica, Cryptosporidium spp.)
Non-infectious Causes
The following are the non-infectious differential diagnoses of E. coli enteritis:
- Acute pancreatitis
- Adrenal insufficiency and Waterhouse-Friedrichsen syndrome
- Allergy (e.g. insect bite allergy or anaphylaxis)
- Appendicitis
- Bowel obstruction
- Diverticulitis
- [[Drug reaction (e.g. antimicrobial agents, antihypertensive therapy, chemotherapy, anticonvulsants)
- Endometriosis
- Familial Mediterranean fever
- Gastrointestinal perforation
- Hyperthyroidism
- Ileus
- Intussusception
- Ischemic colitis
- Ketoacidosis
- Mesenteric ischemia
- Necrotizing enterocolitis
- Ogilvie syndrome
- Peritonitis
- Ruptured abdominal aortic aneurysm
- Spider bite
- Poisoning and toxicity (e.g. carbon monoxide poisoning, organophosphate poisoning, digitoxin toxicity)
- Volvulus
- Urinary tract infection
The table below lists the underlying bacterial pathogens known to cause acute diarrhea:[1][2]
Pathogen | Transmission | Clinical Manifestations | |||
---|---|---|---|---|---|
Fever | Nausea/Vomiting | Abdominal Pain | Bloody Stool | ||
Salmonella | Foodborne transmission, community-acquired | ++ | + | ++ | + |
Shigella | Community-acquired, person-to-person | ++ | ++ | ++ | + |
Campylobacter | Community-acquired, ingestion of undercooked poultry | ++ | + | ++ | + |
Escherichia coli | Foodborne transmission, ingestion of undercooked hamburger meat | - | + | ++ | + (EHEC or EIEC), - (ETEC, EAEC, EPEC) |
Clostridium difficile | Nosocomial spread, antibiotic use | + | ± | + | + |
Yersinia | Community-acquired, foodborne transmission | ++ | + | ++ | + |
Entamoeba histolytica | Travel to or emigration from tropical regions | + | ± | + | ± |
Aeromonas | Ingestion of contaminated water | ++ | + | ++ | + |
Plesiomonas | Ingestion of contaminated water or undercooked shellfish, travel to tropical regions | ± | ++ | + | + |
References
- ↑ Thielman NM, Guerrant RL (2004). "Clinical practice. Acute infectious diarrhea". N Engl J Med. 350 (1): 38–47. doi:10.1056/NEJMcp031534. PMID 14702426.
- ↑ Khan AM, Faruque AS, Hossain MS, Sattar S, Fuchs GJ, Salam MA (2004). "Plesiomonas shigelloides-associated diarrhoea in Bangladeshi children: a hospital-based surveillance study". J Trop Pediatr. 50 (6): 354–6. doi:10.1093/tropej/50.6.354. PMID 15537721.