Splenic marginal zone lymphoma laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [3]
Overview
Laboratory tests for splenic marginal zone lymphoma include complete blood count (CBC), blood chemistry studies, cytogenetic analysis, flow cytometry, immunohistochemistry, genetic testing, FISH, PCR, and immunophenotyping.
Laboratory tests
Laboratory tests for splenic marginal zone lymphoma include:[1]
- Complete blood count (CBC)
- Peripheral Blood Smear
Circulating lymphoma cells are sometimes present in peripheral blood, and they occasionally show short villi at the poles of cells and plasmacytoid differentiation.[2]
- Blood chemistry studies
- Cytogenetic analysis
- Flow cytometry
- Immunohistochemistry
- Genetic testing
- FISH (fluorescence in situ hybridization)
- PCR
- Immunophenotyping
References
- ↑ Splenic marginal zone lymphoma. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov/seertools/hemelymph/51f6cf57e3e27c3994bd5327/ Accessed on December 22,2015
- ↑ [1] Melo JV, Hegde U, Parreira A, Thompson I, Lampert IA, Catovsky D. "Splenic B cell lymphoma with circulating villous lymphocytes: differential diagnosis of B cell leukaemias with large spleens." J Clin Pathol. 1987 Jun;40(6):642-51. PMID: 3497180