Paracoccidioidomycosis natural history, complications and prognosis

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Natural History

The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___. The symptoms of (disease name) typically develop ___ years after exposure to ___. Without treatment, the patient will develop symptoms of ___, which will/ may eventually lead to ___.

Complications

Complications that can develop as a result of PMC are:

• "Worsening of chronic obstructive pulmonary disease (COPD)
• Adrenal gland dysfunction (15-50%)
• dysphonia or laryngeal obstruction, or a combination of the two
• reduced mouth opening
• epilepsy or hydrocephalur, or both (6-25%)"