Osteochondroma causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

There are no established direct causes for osteochondroma. The development of hereditary multiple osteochondroma may be the result of multiple genetic mutations.

Causes

• There are no established direct causes for osteochondroma.
• The development of hereditary multiple osteochondroma may be the result of multiple genetic mutations.
• The related genetic mutations, include:

• Germ line mutation in EXT1 gene located on chromosome 8q24.11-q24.13
• Germ line mutation in EXT2 gene located on chromosome 11p11-12