Mesothelioma differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2], Sujit Routray, M.D. [3]

Overview

Mesothelioma must be differentiated from lung cancer, pulmonary tuberculosis, peritoneal tuberculosis, restrictive cardiomyopathy, and hypertrophic cardiomyopathy.^[1]

Differentiating Mesothelioma from other Diseases

Differentiating Pleural Mesothelioma from other Diseases

Pleural mesothelioma must be differentiated from:^[2]^[3]

Pleural effusion
Benign asbestos-related pleural disease
Peripheral bronchogenic carcinoma
Pleural fibrosis from infective/inflammatory source (e.g. actinomycetes, tuberculosis)
Primary pleural tumors

Secondary lesions that can involve the pleura

Pleural metastases
Thymoma with pleural invasion
Pericardial tumors with pleural invasion
Ewing sarcoma of chest wall with pleural invasion

Differentiating Peritoneal Mesothelioma from other Diseases

Peritoneal mesothelioma must be differentiated from:^[4]^[5]

Peritoneal carcinomatosis
Pseudomyxoma peritonei
Lymphoma with peritoneal involvement
Peritoneal involvement with tuberculosis
Mesenteric panniculitis
Primary peritoneal adenomatoid tumor
Primary peritoneal papillary serous carcinoma
Primary peritoneal serous borderline tumor
Diffuse peritoneal leiomyomatosis
Desmoplastic small round cell tumor arising from the peritoneum
Solitary fibrous tumor arising the peritoneum
Peritoneal lymphangioma

Differentiating Pericardial Mesothelioma from other Diseases

Pericardial mesothelioma must be differentiated from:^[6]

References

↑ Mesothelioma. Radiopaedia. http://radiopaedia.org/articles/mesothelioma. Accessed on 13th January, 2016. http://radiopaedia.org/articles/mesothelioma
↑ Differential diagnosis of mesothelioma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/mesothelioma. Accessed on February 12, 2016
↑ Dr Yuranga Weerakkody et al. Radiopaedia 2016. http://radiopaedia.org/articles/pleural-tumours. Accessed on February 12, 2016
↑ Differential diagnosis of peritoneal mesothelioma. Dr Alexandra Stanislavsky et al. Radiopaedia 2016. http://radiopaedia.org/articles/peritoneal-mesothelioma. Accessed on February 12, 2016
↑ Primary peritoneal neoplasms. Dr Praveen Jha and Radswiki et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-peritoneal-neoplasms. Accessed on February 12, 2016
↑ Seek a Second Opinion to Avoid Misdiagnosis of Pericardial Mesothelioma. Asbestos.com 2016. http://www.asbestos.com/mesothelioma/pericardial.php. Accessed on February 12, 2016

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[1] Mesothelioma. Radiopaedia. http://radiopaedia.org/articles/mesothelioma. Accessed on 13th January, 2016. http://radiopaedia.org/articles/mesothelioma

[ddxmesothelioma1-2] Differential diagnosis of mesothelioma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/mesothelioma. Accessed on February 12, 2016

[pleuraltumors1-3] Dr Yuranga Weerakkody et al. Radiopaedia 2016. http://radiopaedia.org/articles/pleural-tumours. Accessed on February 12, 2016

[ddxperitonealmesotheliomadifferentialdiagnosis1-4] Differential diagnosis of peritoneal mesothelioma. Dr Alexandra Stanislavsky et al. Radiopaedia 2016. http://radiopaedia.org/articles/peritoneal-mesothelioma. Accessed on February 12, 2016

[Primaryperitonealneoplasms1-5] Primary peritoneal neoplasms. Dr Praveen Jha and Radswiki et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-peritoneal-neoplasms. Accessed on February 12, 2016

[ddxpericardialmesotheliomadifferential1diagnosis1-6] Seek a Second Opinion to Avoid Misdiagnosis of Pericardial Mesothelioma. Asbestos.com 2016. http://www.asbestos.com/mesothelioma/pericardial.php. Accessed on February 12, 2016

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