Lymphogranuloma venereum history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nate Michalak, B.A.
Overview
The most common symptom of primary LGV is a painless papule or ulcer. Secondary LGV is characterized by painful inguinal and/or femoral lymphadenopathy, or Iliac and/or perirectal lymphadenopathy in patients with rectal exposure. Proctolcolits may also develop at this stage. Tertiary LGV symptoms include Lymphatic and rectal fibrosis, genital elephantiasis, esthiomene (chronic ulcerative disease of vulva), edema, tenesmus and rectal discharge. LGV may spread systemically and cause the following symptoms: fever, chills, malaise, myalgia, arthralgia, arthritis, hepatitis or perihepatitis, and pneumonitis.
Symptoms
Primary LGV
Secondary LGV
- Painful inguinal and/or femoral lymphadenopathy, usually unilateral[2]
- Iliac and/or perirectal lymphadenopathy in patients with rectal exposure
- Hemorrhagic proctocolitis
- Lower abdominal or low-back pain[3]
Tertiary LGV
- Lymphatic and rectal fibrosis[4]
- Lymphorroids (hemorrhoid-like swellings of lymphatics)
- Chronic edema
- Genital elephantiasis[1]
- Esthiomene (chronic ulcerative disease of vulva)
- Frozen pelvis syndrome[5]
- Tenesmus
- Bloody purulent rectal discharge
- Rectal pain
- Hyperplasia of intestinal and perirectal lymphatic tissue[2]
Systemic Symptoms
- Fever
- Chills
- Malaise
- Myalgia
- Arthralgia
- Arthritis
- Hepatitis or perihepatitis
- Pneumonitis
- Cardiac involvment (rare)
- Aseptic meningitis (rare)
- Ocular inflammatory disease (rare)[2]
References
- ↑ 1.0 1.1 Mabey, D (2002). "Lymphogranuloma venereum". Sexually Transmitted Infections. 78 (2): 90–92. doi:10.1136/sti.78.2.90. ISSN 1368-4973.
- ↑ 2.0 2.1 2.2 Ceovic R, Gulin SJ (2015). "Lymphogranuloma venereum: diagnostic and treatment challenges". Infect Drug Resist. 8: 39–47. doi:10.2147/IDR.S57540. PMC 4381887. PMID 25870512.
- ↑ de Vries HJ, Zingoni A, White JA, Ross JD, Kreuter A (2013). "2013 European Guideline on the management of proctitis, proctocolitis and enteritis caused by sexually transmissible pathogens". Int J STD AIDS. 25 (7): 465–474. doi:10.1177/0956462413516100. PMID 24352129.
- ↑ Lynch CM, Felder TL, Schwandt RA, Shashy RG (1999). "Lymphogranuloma venereum presenting as a rectovaginal fistula". Infect Dis Obstet Gynecol. 7 (4): 199–201. doi:10.1155/S1064744999000344. PMC 1784745. PMID 10449269.
- ↑ Van der Bij AK, Spaargaren J, Morré SA, Fennema HS, Mindel A, Coutinho RA; et al. (2006). "Diagnostic and clinical implications of anorectal lymphogranuloma venereum in men who have sex with men: a retrospective case-control study". Clin Infect Dis. 42 (2): 186–94. doi:10.1086/498904. PMID 16355328.