Non small cell lung cancer other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

Other diagnostic modalities for non-small cell lung cancer, include: thoracotomy, bronchoscopy, mediastinoscopy, and transthoracic percutaneous fine needle aspiration.

Other Diagnostic Studies

• There are numerous diagnostic modalities which allow staging of mediastinal lymph nodes.
• The table below demonstrates the different types of diagnostic modalities in non small cell lung cancer arranged from the most to the least invasive.

Procedure	Advantages	Disadvantages
Endobronchial ultrasound (EBUS)	Direct visualization of lymph node stations. Complements endoscopic ultrasound: covers lymph node stations 2R and 4R which are difficult to access by endoscopic ultrasound Lower false-negative rate than with blind transbronchial fine needle aspiration and fewer complications	More invasive than endoscopic ultrasound, few practitioners, but rapidly growing in popularity
Endoscopic ultrasound (EUS)	Least invasive modality Uses the esophagus to access mediastinal lymph nodes Excellent for staging lymph nodes Useful for station 2L and 4L, L adrenal, celiac lymph node	Cannot reliably access right sided paratracheal lymph node stations 2 R and 4R Accurate discrimination of primary hilar tumors and involved lymph nodes is important

References

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