Donovanosis historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nate Michalak, B.A.
Overview
Historical Perspective
- Donovanosis was first called serpiginous ulcer, dating back to 1882.[1]
- In 1905, Charles Donovan discovered intracellular bodies as the cause of this ulcer; the nature of the bodies was unknown and they were referred to as "Donovan bodies."[2]
- Calymmatobacterium granulomatis was presumed to be the causative agent of donovanosis by Aragão & Vianna in 1913.
- However, gene sequencing of bacteria in Donovan bodies by Carter et al. revealed the caustive agent to be Klebsiella granulomatis.[3]
References
- ↑ McLeod K. (1882). "Precis of operations performed in the wards of the first surgeon, Medical College Hospital, during the year 1881". Ind Med Gaz. 11: 113.
- ↑ Donovan, C. (1905). "Ulcerating Granuloma of the Pudenda". Ind Med Gaz. 40: 414.
- ↑ Carter JS, Bowden FJ, Bastian I, Myers GM, Sriprakash KS, Kemp DJ (1999). "Phylogenetic evidence for reclassification of Calymmatobacterium granulomatis as Klebsiella granulomatis comb. nov". Int J Syst Bacteriol. 49 Pt 4: 1695–700. doi:10.1099/00207713-49-4-1695. PMID 10555350.