Mast cell tumor classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Classification
Based on the affected organ(s), mast cell tumor may be classified into three subtypes:
- Cutaneous mastocytosis
- Systemic mastocytosis
- Localized mastocytosis
Mast cell tumor may be classified according to WHO classification into seven subtypes:[1]
- Cutaneous mastocytosis
- Urticaria pigmentosa
- Maculopapular cutaneous mastocytosis
- Diffuse cutaneous mastocytosis
- Mastocytoma of skin
- Indolent systemic mastocytosis
- Smoldering systemic mastocytosis
- Isolated bone marrow mastocytosis
- Systemic mastocytosis with an associated (clonal) hematologic non–mast cell lineage disease
- Aggressive systemic mastocytosis
- Lymphadenopathic systemic mastocytosis with eosinophilia
- Mast cell leukemia
- Typical mast cell leukemia
- Aleukemic mast cell leukemia
- Mast cell sarcoma
- Extracutaneous mastocytoma
References
- ↑ Patnaik MM, Rindos M, Kouides PA, Tefferi A, Pardanani A (2007). "Systemic mastocytosis: a concise clinical and laboratory review". Arch Pathol Lab Med. 131 (5): 784–91. doi:10.1043/1543-2165(2007)131[784:SMACCA]2.0.CO;2. PMID 17488167.