Seminoma natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Common complications of seminoma include:^[2]

The International Germ Cell Cancer Consensus Group (IGCCCG) developed a classification system based on prognostic factors. It indicates how well the cancer is expected to respond to treatment. This system helps physicians make decisions about treatment for advanced germ cell tumors.^[3]
Prognosis of seminoma is good for all stages with greater than 90% cure rate.^[4]
IGCCCG divides seminoma into two prognosis groups:^[3]


Prognosis group	Seminoma

Good	There are no distant metastases other than to the lungs. Alpha-fetoprotein (AFP) is normal and other serum tumor markers can be any level.
Intermediate	There are distant metastases to organs other than the lungs. AFP is normal and other serum tumor markers can be any level.

↑ Cancerous tumours of the testicle. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/testicular/testicular-cancer/cancerous-tumours/?region=on. Accessed on February 26, 2016
↑ Testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on March 3, 2016
↑ ^3.0 ^3.1 Prognosis and survival for testicular cancer. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/testicular/prognosis-and-survival/?region=on. Accessed on February 29, 2016
↑ Treatment and prognosis of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on March 2, 2016