Donovanosis pathophysiology

Donovanosis Microchapters
Home
Patient Information
Overview
Historical Perspective
Pathophysiology
Causes
Classification
Differentiating Donovanosis from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Treatment
Medical Therapy
Prevention
Case Studies
Case #1
Donovanosis pathophysiology On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
slides
Images
American Roentgen Ray Society Images of Donovanosis pathophysiology All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Donovanosis pathophysiology
CDC on Donovanosis pathophysiology
Donovanosis pathophysiology in the news
Blogs on Donovanosis pathophysiology
Directions to Hospitals Treating Donovanosis
Risk calculators and risk factors for Donovanosis pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]; Nate Michalak, B.A.

Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.

Microscopic Pathology

• Donovan bodies (K. granulomatis) are seen within phagosomes or in the cytoplasm of monocytes or histocytes.
• Morphology of Donovan bodies:

• Pleomorphic ranging from coccus to bacillus
• 1-2 X 0.5-0.7 μm
• May or may not be capsulated
• Non-motile

• Epidermis of lesion borders show a degree of hyperplasia.
• A dense infiltrate of plasma cells is seen in the dermis.