Mast cell tumor physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2]

Physical Examination

Vital signs

• Hypotension
• Tachycardia

Skin

• Urticaria pigmentosa:

• Fixed, reddish brown lesions appears as maculo-papules, plaques, nodules, or blisters.
• Urticaria Pigmentosa (UP) lesions tend to be larger, better delineated, and more hyperpigmented in children, as compared to adults, who tend to have numerous small lesions that coalesce to form mottled areas.
• The trunk and thigh are more commonly involved with sparing of face, palms and soles.

• Darier’s sign:

• Lesions urticate in response to physical irritation.

• Diffuse Cutaneous Mastocytosis

• Diffuse infiltrative yellow-orange xanthogranuloma-like subcutaneous nodules, or as a widespread urticarial eruption with bullae and redness.

Abdomen

• Hepatomegaly
• Splenomegaly

• 

  Mastocytoma.
  Adapted from Atlas<ref name="www.atlasdermatologico.com.br">"Dermatology Atlas".

• 

  Mastocytoma.
  Adapted from Atlas<ref name="www.atlasdermatologico.com.br">"Dermatology Atlas".

• 

  Mastocytoma.
  Adapted from Atlas<ref name="www.atlasdermatologico.com.br">"Dermatology Atlas".

• 

  Mastocytoma.
  Adapted from Atlas<ref name="www.atlasdermatologico.com.br">"Dermatology Atlas".

References