Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Classification
Retinitis Pigmentosa
Classification
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Clinical Manifestations
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Nyctalopia
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- Occurs early on during the clinical course of Retinitis Pigmentosa.
- Night blindness occurs due to the loss of rod function.
- Nyctalopia can be an indicator of the eventually clinical severity of the complications associated with retinitis.
- Early onset of severe complications typically indicates more severe complications later on during the clinical course.
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Fundus
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- Defective rod cell response, although fundus appears normal
- Arteriolar narrowing
- Intraretinal pigmentation
- Loss of pigment in pigment epithelium
- Intraretinal clumping due to the accumulation of melanin
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Visual acuity
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- Macular lesions
- Defective cone cell function
- Loss of central acuity
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Sector RP
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- Changes may be observed in specific halves or quadrants of the fundus
- Less severe defects in the visual field
- Sectorial disease with the long term potential of widespread disease
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Retinitis Pigmentosa and Pregnancy
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- Women previously diagnosed with retinitis pigmentosa may report an overall decrease in vision during pregnancy.
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Infectious Agents
References