Von Willebrand disease overview
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Von Willebrand disease Microchapters |
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Von Willebrand disease overview On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Von Willebrand disease (vWD) is the most common hereditary coagulation abnormality described in humans. It affects up to 1% of the population, although most cases are mild. It arises from a qualitative or quantitative deficiency of von Willebrand factor (vWF), a multimeric protein that is required for platelet adhesion .