Cogan syndrome

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Synonyms and keywords: Oculovestibuloauditory syndrome

Overview

Cogan syndrome is a rare disorder characterized by recurrent inflammation of the front of the eye (the cornea) and often fever, fatigue, and weight loss, episodes of dizziness, and hearing loss. It can lead to deafness or blindness if untreated. The classic form of the disease was first described by D.G. Cogan in 1945.

History

In 1945 D.G. Cogan first described the "nonsyphilitic interstitial keratitis and vestibuloauditory symptoms" that would later bear his name (Cogan, 1945). In 1963, the atypical form of Cogan syndrome was first described (Bennett, 1963)

Related disorders

• McCabe disease

References

• Cogan DG (1945). "Syndrome of nonsyphilitic interstitial keratitis and vestiboloauditory symptoms". Arch Ophthalmol. 33: 144–9.

• Bennett FM (1963). "Bilateral recurrent episcleritis associated with posterior corneal changes, vestibulo-auditory symptoms and rheumatoid arthritis". Am J Ophthalmol. 55: 815–8. PMID 13967466