Diphtheria history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]

Overview

History and Symptoms

Respiratory diphtheria presents with a wide range of systemic and respiratory symptoms, which include:^[1]

Respiratory Symptoms

Sore throat: most common presenting symptom
Cough
Runny nose (rhinorrhea)
Hoarseness of voice
Nasal obstruction
Coughing of blood (hemoptysis)

Systemic Symptoms

Fever
Chills
Malaise
Palpitations
Nausea
Vomiting
Muscle pain (myalgia)
Neck swelling due to cervical adenopathy

Cutaneous (Skin) Diphtheria

Cutaneous diphtheria usually presents with ulcers or pustular lesions, which can involve different parts of the body. They can have a grayish-white pseudomembrane, similar to tonsillar exudates of respiratory diphtheria.^[2]

References

↑ Dobie RA, Tobey DN (1979). "Clinical features of diphtheria in the respiratory tract". JAMA. 242 (20): 2197–201. PMID 490806.
↑ Rappold LC, Vogelgsang L, Klein S, Bode K, Enk AH, Haenssle HA (2016). "Primary cutaneous diphtheria: management, diagnostic workup, and treatment as exemplified by a rare case report". J Dtsch Dermatol Ges. 14 (7): 734–6. doi:10.1111/ddg.12722. PMID 27373251.

Template:WikiDoc Sources

[pmid490806-1] Dobie RA, Tobey DN (1979). "Clinical features of diphtheria in the respiratory tract". JAMA. 242 (20): 2197–201. PMID 490806.

[pmid27373251-2] Rappold LC, Vogelgsang L, Klein S, Bode K, Enk AH, Haenssle HA (2016). "Primary cutaneous diphtheria: management, diagnostic workup, and treatment as exemplified by a rare case report". J Dtsch Dermatol Ges. 14 (7): 734–6. doi:10.1111/ddg.12722. PMID 27373251.

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