Human papillomavirus physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

Physical examination

Cutaneous lesions

Warts

They are well demarcated, exophytic, hyperkeratotic papules or plaques with a rough surface that are usually located on the fingers or lateral surface of the hands that could be single or in groups.

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  Common wart. Adapted from Dermatology Atlas.

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  Common wart. Adapted from Dermatology Atlas.

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  Plantar wart. Adapted from Dermatology Atlas.

Epidermodysplasia verruciformis

Characterized by the growth of scaly macules and papules, that may become hypertrophic and coalescent particularly on the hands and upper trunk in children.

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  Epidermodysplasia verruciformis. Adapted from Dermatology Atlas.

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  Epidermodysplasia verruciformis. Adapted from Dermatology Atlas.

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  Epidermodysplasia verruciformis. Adapted from Dermatology Atlas.

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  Epidermodysplasia verruciformis. Adapted from Dermatology Atlas.

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  Epidermodysplasia verruciformis. Adapted from Dermatology Atlas.

Anogenital lesions

Intraepithelial neoplasia

Digital palpation of the vagina to assess for thickening or irregularity of the vaginal wall and a thorough colposcopic assessment of the entire vagina must be perform, however physical examination of patients with early stage is usually unremarkable, but after the insertion of a speculum and the application of acetic acid, lesions will appear as raised or flat white, granular epithelium with sharply demarcated borders and may contain areas of vascular punctation.

Condylomata acuminata

Its shape ranges from smooth flattened papule to a verrucous, papilliform appearance may be skin-colored, brown or whitish may also present as pedunculated or broad-based papillomas up to several centimeters in diameter or as large confluent plaques. Female and male genital area and perianal may be affected.

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  Condyloma acuminata

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  Condyloma acuminata

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  Condyloma acuminata. Adapted from Dermatology Atlas.

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  Condyloma acuminata. Adapted from Dermatology Atlas.

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  Condyloma acuminata. Adapted from Dermatology Atlas.

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  Condyloma acuminata. Adapted from Dermatology Atlas.

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  Condyloma acuminata. Adapted from Dermatology Atlas.

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  Condyloma acuminata. Adapted from Dermatology Atlas.

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  Condyloma acuminata. Adapted from Dermatology Atlas.