Strep throat medical therapy

Strep throat Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]

Medical therapy

The mainstay of therapy for Strep throat is medical therapy. Treatment will help reduce symptoms, minimize transmission, and reduce the likelihood of complications. Antibiotic treatment recommended for strep throat include the following:

For individuals without penicillin allergy
Drug, Route	Recommended dose	Duration
Penicillin V, oral	Children: 250 mg twice daily or 3 times daily; adolescents and adults: 250 mg 4 times daily or 500 mg twice daily	10 days
Amoxicillin, oral	50 mg/kg once daily (max = 1000 mg); Alternate:25 mg/kg (max = 500 mg) twice daily	10 days
Benzathine penicillin G, intramuscular	<27 kg: 600 000 U; ≥27 kg: 1 200 000 U	1 dose
For individuals with penicillin allergy
Cephalexin, oral	20 mg/kg/dose twice daily (max = 500 mg/dose)	10 days
Cefadroxil, oral	30 mg/kg once daily (max = 1 g)	10 days
Clindamycin, oral	7 mg/kg/dose 3 times daily (max = 300 mg/dose)	10 days
Azithromycin, oral	12 mg/kg once daily (max = 500 mg)	5 days
Clarithromycin, oral	7.5 mg/kg/dose twice daily (max = 250 mg/dose)	10 days

References

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