Differentiating Churg-Strauss syndrome from other diseases

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Differentiating Churg-Strauss syndrome from other Diseases

• Differentiation of Churg-Strauss syndrome from Wegener's granulomatosis can be difficult, though the increasing use of ANCA assays has made the distinction more routine. Wegener's is closely associated with c-ANCA, unlike Churg-Strauss which shows elevations of p-ANCA.
• Churg-Strauss syndrome was once considered a type of Polyarteritis nodosa (PAN) due to their similar morphologies.