Stress cardiomyopathy natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Natural History

Provided that patients survive the initial insult without any complications, most patients recover and have a normalized cardiac function within a few weeks.^[1]^[2]

Complications

Complications of stress cardiomyopathy include:^[1]^[3]^[4]

Heart failure
Pulmonary edema
Cardiogenic shock
Arrythmias, mainly QT prolongation
Left ventricular mural thrombus
Mitral valve dysfunction pulmonary embolism
LV free wall rupture
Heart rupture
Death

Prognosis

The prognosis of stress cardiomyopathy is generally good, even without medical therapy.^[4] Most patients have a restored cardiac function within a few weeks.^[2] However, fatal complications such as LV free wall rupture and heart rupture may occur and mortality rate in patients with stress cardiomyopathy ranges from 0-8%.^[1]^[4]

References

↑ ^1.0 ^1.1 ^1.2 Akashi YJ, Goldstein DS, Barbaro G, Ueyama T (2008). "Takotsubo cardiomyopathy: a new form of acute, reversible heart failure". Circulation. 118 (25): 2754–62. doi:10.1161/CIRCULATIONAHA.108.767012. PMC 4893309. PMID 19106400.
↑ ^2.0 ^2.1 Prasad A, Lerman A, Rihal CS (2008). "Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction". Am. Heart J. 155 (3): 408–17. doi:10.1016/j.ahj.2007.11.008. PMID 18294473.
↑ Omerovic E (2011). "How to think about stress-induced cardiomyopathy?--Think "out of the box"!". Scand. Cardiovasc. J. 45 (2): 67–71. doi:10.3109/14017431.2011.565794. PMID 21401402.
↑ ^4.0 ^4.1 ^4.2 Brenner ZR, Powers J (2008). "Takotsubo cardiomyopathy". Heart Lung. 37 (1): 1–7. doi:10.1016/j.hrtlng.2006.12.003. PMID 18206521.

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[pmid19106400-1] 1.0 ^1.1 ^1.2 Akashi YJ, Goldstein DS, Barbaro G, Ueyama T (2008). "Takotsubo cardiomyopathy: a new form of acute, reversible heart failure". Circulation. 118 (25): 2754–62. doi:10.1161/CIRCULATIONAHA.108.767012. PMC 4893309. PMID 19106400.

[pmid18294473-2] 2.0 ^2.1 Prasad A, Lerman A, Rihal CS (2008). "Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction". Am. Heart J. 155 (3): 408–17. doi:10.1016/j.ahj.2007.11.008. PMID 18294473.

[pmid21401402-3] Omerovic E (2011). "How to think about stress-induced cardiomyopathy?--Think "out of the box"!". Scand. Cardiovasc. J. 45 (2): 67–71. doi:10.3109/14017431.2011.565794. PMID 21401402.

[pmid18206521-4] 4.0 ^4.1 ^4.2 Brenner ZR, Powers J (2008). "Takotsubo cardiomyopathy". Heart Lung. 37 (1): 1–7. doi:10.1016/j.hrtlng.2006.12.003. PMID 18206521.

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