Cystitis secondary prevention
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Overview
Secondary prophylaxis of Cystitis is useful to prevent recurrent cystitis. It is more beneficial in patients in which Cystitis is associated with sexual intercourse, a structural defect or a disease like Diabetes that can lead to recurrent infections.
Secondary Prevention
The secondary Prevention of Cystitis includes the prophylaxis to prevent recurrent cystitis.
Antimicrobial Prophylaxis
- Prophylactic therapy using antimicrobial agents may be considered among women with recurrent episodes of cystitis that are associated with sexual activity.
- The following regimens may be used as single doses prior to sexual activity.
- Prophylactic Therapy:[1]
- Preferred regimen (1): Fosfomycin tromethamine 3 g PO in a single dose
- Preferred regimen (2): Nitrofurantoin monohydrate/macrocrystals 100 mg PO in a single dose
- Preferred regimen (3): Trimethoprim-Sulfamethoxazole 160/800 mg PO double-strength tablet bid in a single dose
- Preferred regimen (4): Trimethoprim 100 mg PO bid in a single dose
- Alternative regimen (1): Ciprofloxacin 250 mg PO bid in a single dose
- Alternative regimen (2): Levofloxacin 250 mg PO qd in a single dose
- Alternative regimen (3): Norfloxacin 400 mg PO bid in a single dose
- Alternative regimen (4): Gatifloxacin 200 mg PO qd in a single dose
References
- ↑ Gupta K, Hooton TM, Naber KG, Wullt B, Colgan R, Miller LG; et al. (2011). "International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases". Clin Infect Dis. 52 (5): e103–20. doi:10.1093/cid/ciq257. PMID 21292654.