Tropical sprue overview
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Tropical sprue Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shivani Chaparala M.B.B.S [2]
Synonyms and keywords: Chronic diarrhea, Intestinal malabsorption, Tropical malabsorption, Postinfective malabsorption, Tropical enteropathy, Tropical diarrhea, Military diarrhea, Cachectic diarrhea, Psilosis, Aphthae tropical.
Overview
Tropical sprue is an acquired malabsorption disease of unknown etiology commonly found in the tropical regions, marked with abnormal flattening of the villi and inflammation of the lining of the small intestine. Ghoshal et al. defined a group of patients with TS by strict clinical and pathological criteria and show that aerobic bacteria contaminate the small bowel in patients with TS and that these patients have a prolonged orocecal transit time (OCTT) compared with healthy control subjects. It differs significantly from coeliac sprue.