Rotavirus infection pathophysiology

Rotavirus infection Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Pathophysiology

Transmission

• Rotavirus spreads easily among infants and young children. Children can spread the virus both before and after they become sick with diarrhea. They can also pass rotavirus to family members and other people with whom they have close contact.
• People who are infected with rotavirus shed rotavirus in their feces (poop) - this is often how the virus spreads from a person’s body to other people and into the environment. They shed the virus most when they are sick and during the first 3 days after they recover.
• The virus spreads by the fecal-oral route; this means the virus is shed by an infected person and then enters a susceptible person’s mouth to cause infection. Rotavirus can be spread by the following:
  • Hands
  • Objects (toys, surfaces)
  • Food
  • Water